The term “Nicotine salt” also known as nic salt just refers to the scientific definition. It doesn’t mean it’s infused with the tasty mineral you sprinkle on your mac and cheese. In chemical terms, a salt results when an acid reacts with a base. Simply put, nicotine salts are made by mixing pure nicotine (base) with certain kinds of acids. I know what you're thinking right about now, Acids? That sounds worse? Actually, nicotine salts exist in tobacco, naturally. So if you have smoked a cigarette you have experienced nicotine salt.